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Target
Regulator of G-protein signaling 8
Ligand
BDBM47777
Substrate
n/a
Meas. Tech.
Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 8
Synonyms:
RGS8 | RGS8_HUMAN | Regulator of G-protein signaling 8 (RGS8)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
20925.80
Organism:
Homo sapiens (Human)
Description:
gi_74355113
Residue:
180
Sequence:
MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPREVNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS
  
Inhibitor
Name:
BDBM47777
Synonyms:
MLS000375249 | N-[1-[1-[2-[4-(diethylamino)anilino]-2-keto-ethyl]benzimidazol-2-yl]ethyl]-4-methyl-benzamide | N-[1-[1-[2-[4-(diethylamino)anilino]-2-oxoethyl]-2-benzimidazolyl]ethyl]-4-methylbenzamide | N-[1-[1-[2-[4-(diethylamino)anilino]-2-oxoethyl]benzimidazol-2-yl]ethyl]-4-methylbenzamide | N-[1-[1-[2-[[4-(diethylamino)phenyl]amino]-2-oxidanylidene-ethyl]benzimidazol-2-yl]ethyl]-4-methyl-benzamide | SMR000254502 | cid_4831653
Type:
Small organic molecule
Emp. Form.:
C29H33N5O2
Mol. Mass.:
483.6046
SMILES:
CCN(CC)c1ccc(NC(=O)Cn2c(nc3ccccc23)C(C)NC(=O)c2ccc(C)cc2)cc1
Structure:
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