Reaction Details Report a problem with these data
Target
Regulator of G-protein signaling 8
Ligand
BDBM47785
Substrate
n/a
Meas. Tech.
Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 8
Synonyms:
RGS8 | RGS8_HUMAN | Regulator of G-protein signaling 8 (RGS8)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
20925.80
Organism:
Homo sapiens (Human)
Description:
gi_74355113
Residue:
180
Sequence:
MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPREVNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS
  
Inhibitor
Name:
BDBM47785
Synonyms:
2-(ethylthio)-N-(3-pyridinylmethyl)benzamide | 2-(ethylthio)-N-(3-pyridylmethyl)benzamide | 2-ethylsulfanyl-N-(pyridin-3-ylmethyl)benzamide | MLS000764635 | SMR000290240 | cid_970318
Type:
Small organic molecule
Emp. Form.:
C15H16N2OS
Mol. Mass.:
272.365
SMILES:
CCSc1ccccc1C(=O)NCc1cccnc1
Structure:
Search PDB for entries with ligand similarity: