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Target
Regulator of G-protein signaling 8
Ligand
BDBM47829
Substrate
n/a
Meas. Tech.
Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 8
Synonyms:
RGS8 | RGS8_HUMAN | Regulator of G-protein signaling 8 (RGS8)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
20925.80
Organism:
Homo sapiens (Human)
Description:
gi_74355113
Residue:
180
Sequence:
MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPREVNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS
  
Inhibitor
Name:
BDBM47829
Synonyms:
(5Z)-5-[ethoxy(hydroxy)methylene]-2-[3-(trifluoromethyl)phenyl]-2-thiazolin-4-one | (5Z)-5-[ethoxy(hydroxy)methylidene]-2-[3-(trifluoromethyl)phenyl]-1,3-thiazol-4-one | (5Z)-5-[ethoxy(hydroxy)methylidene]-2-[3-(trifluoromethyl)phenyl]-4-thiazolone | (5Z)-5-[ethoxy(oxidanyl)methylidene]-2-[3-(trifluoromethyl)phenyl]-1,3-thiazol-4-one | MLS000851000 | SMR000457017 | cid_5922688 | ethyl 4-hydroxy-2-[3-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxylate
Type:
Small organic molecule
Emp. Form.:
C13H10F3NO3S
Mol. Mass.:
317.284
SMILES:
CCOC(=O)c1sc(nc1O)-c1cccc(c1)C(F)(F)F
Structure:
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