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Target
Regulator of G-protein signaling 16
Ligand
BDBM47761
Substrate
n/a
Meas. Tech.
Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 16
Synonyms:
RGS16 | RGS16_HUMAN | RGSR | Regulator of G-protein signaling 16 (RGS16) | regulator of G-protein signalling 16
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22748.87
Organism:
Homo sapiens (Human)
Description:
gi_156416009
Residue:
202
Sequence:
MCRTLAAFPTTCLERAKEFKTRLGIFLHKSELGCDTGSTGKFEWGSKHSKENRNFSEDVLGWRESFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHQIFEEFICSEAPKEVNIDHETHELTRMNLQTATATCFDAAQGKTRTLMEKDSYPRFLKSPAYRDLAAQASAASATLSSCSLDEPSHT
  
Inhibitor
Name:
BDBM47761
Synonyms:
2-(5-nitropyridin-2-yl)sulfanylpyridin-3-amine | 2-[(5-nitro-2-pyridinyl)thio]-3-pyridinamine | 3-amino-2-({5-nitropyridin-2-yl}thio)pyridine | MLS000702477 | SMR000226877 | [2-[(5-nitro-2-pyridyl)thio]-3-pyridyl]amine | cid_901969
Type:
Small organic molecule
Emp. Form.:
C10H8N4O2S
Mol. Mass.:
248.261
SMILES:
Nc1cccnc1Sc1ccc(cn1)[N+]([O-])=O
Structure:
Search PDB for entries with ligand similarity: