Reaction Details Report a problem with these data
Target
Regulator of G-protein signaling 16
Ligand
BDBM47763
Substrate
n/a
Meas. Tech.
Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 16
Synonyms:
RGS16 | RGS16_HUMAN | RGSR | Regulator of G-protein signaling 16 (RGS16) | regulator of G-protein signalling 16
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22748.87
Organism:
Homo sapiens (Human)
Description:
gi_156416009
Residue:
202
Sequence:
MCRTLAAFPTTCLERAKEFKTRLGIFLHKSELGCDTGSTGKFEWGSKHSKENRNFSEDVLGWRESFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHQIFEEFICSEAPKEVNIDHETHELTRMNLQTATATCFDAAQGKTRTLMEKDSYPRFLKSPAYRDLAAQASAASATLSSCSLDEPSHT
  
Inhibitor
Name:
BDBM47763
Synonyms:
1-(4-chloranyl-2,5-dimethoxy-phenyl)sulfonyl-2-ethyl-imidazole | 1-(4-chloro-2,5-dimethoxy-phenyl)sulfonyl-2-ethyl-imidazole | 1-(4-chloro-2,5-dimethoxyphenyl)sulfonyl-2-ethylimidazole | 1-[(4-chloro-2,5-dimethoxyphenyl)sulfonyl]-2-ethyl-1H-imidazole | MLS000705517 | SMR000231827 | cid_850092
Type:
Small organic molecule
Emp. Form.:
C13H15ClN2O4S
Mol. Mass.:
330.787
SMILES:
CCc1nccn1S(=O)(=O)c1cc(OC)c(Cl)cc1OC
Structure:
Search PDB for entries with ligand similarity: