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Target
Regulator of G-protein signaling 16
Ligand
BDBM47793
Substrate
n/a
Meas. Tech.
Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 16
Synonyms:
RGS16 | RGS16_HUMAN | RGSR | Regulator of G-protein signaling 16 (RGS16) | regulator of G-protein signalling 16
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22748.87
Organism:
Homo sapiens (Human)
Description:
gi_156416009
Residue:
202
Sequence:
MCRTLAAFPTTCLERAKEFKTRLGIFLHKSELGCDTGSTGKFEWGSKHSKENRNFSEDVLGWRESFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHQIFEEFICSEAPKEVNIDHETHELTRMNLQTATATCFDAAQGKTRTLMEKDSYPRFLKSPAYRDLAAQASAASATLSSCSLDEPSHT
  
Inhibitor
Name:
BDBM47793
Synonyms:
2-(4-methyl-N-(4-methylsulfanylphenyl)sulfonylanilino)-N-[(1-methylpiperidin-4-ylidene)amino]acetamide | 2-(4-methyl-N-[4-(methylthio)phenyl]sulfonyl-anilino)-N-[(1-methyl-4-piperidylidene)amino]acetamide | 2-(4-methyl-N-[4-(methylthio)phenyl]sulfonylanilino)-N-[(1-methyl-4-piperidinylidene)amino]acetamide | 2-[(4-methylphenyl)-(4-methylsulfanylphenyl)sulfonyl-amino]-N-[(1-methylpiperidin-4-ylidene)amino]ethanamide | MLS000681786 | SMR000312829 | Structure possibly contains amino acid derivative which is not supported in current version! | cid_4473031
Type:
Small organic molecule
Emp. Form.:
C22H28N4O3S2
Mol. Mass.:
460.613
SMILES:
[#6]-[#16]-c1ccc(cc1)S(=O)(=O)[#7](-[#6]-[#6](=O)-[#7]\[#7]=[#6]-1\[#6]-[#6]-[#7](-[#6])-[#6]-[#6]-1)-c1ccc(-[#6])cc1
Structure:
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