Reaction Details Report a problem with these data
Target
Regulator of G-protein signaling 16
Ligand
BDBM47794
Substrate
n/a
Meas. Tech.
Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 16
Synonyms:
RGS16 | RGS16_HUMAN | RGSR | Regulator of G-protein signaling 16 (RGS16) | regulator of G-protein signalling 16
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22748.87
Organism:
Homo sapiens (Human)
Description:
gi_156416009
Residue:
202
Sequence:
MCRTLAAFPTTCLERAKEFKTRLGIFLHKSELGCDTGSTGKFEWGSKHSKENRNFSEDVLGWRESFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHQIFEEFICSEAPKEVNIDHETHELTRMNLQTATATCFDAAQGKTRTLMEKDSYPRFLKSPAYRDLAAQASAASATLSSCSLDEPSHT
  
Inhibitor
Name:
BDBM47794
Synonyms:
MLS000419420 | N-(5-chloranyl-4-methyl-1,3-benzothiazol-2-yl)ethanamide | N-(5-chloro-4-methyl-1,3-benzothiazol-2-yl)acetamide | SMR000320254 | cid_2150683
Type:
Small organic molecule
Emp. Form.:
C10H9ClN2OS
Mol. Mass.:
240.709
SMILES:
CC(=O)Nc1nc2c(C)c(Cl)ccc2s1
Structure:
Search PDB for entries with ligand similarity: