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Target
Regulator of G-protein signaling 16
Ligand
BDBM47796
Substrate
n/a
Meas. Tech.
Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 16
Synonyms:
RGS16 | RGS16_HUMAN | RGSR | Regulator of G-protein signaling 16 (RGS16) | regulator of G-protein signalling 16
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22748.87
Organism:
Homo sapiens (Human)
Description:
gi_156416009
Residue:
202
Sequence:
MCRTLAAFPTTCLERAKEFKTRLGIFLHKSELGCDTGSTGKFEWGSKHSKENRNFSEDVLGWRESFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHQIFEEFICSEAPKEVNIDHETHELTRMNLQTATATCFDAAQGKTRTLMEKDSYPRFLKSPAYRDLAAQASAASATLSSCSLDEPSHT
  
Inhibitor
Name:
BDBM47796
Synonyms:
(E)-1-(3,5-dimethyl-1-piperidinyl)-3-(5-nitro-2-thiophenyl)-2-propen-1-one | (E)-1-(3,5-dimethylpiperidin-1-yl)-3-(5-nitrothiophen-2-yl)prop-2-en-1-one | (E)-1-(3,5-dimethylpiperidino)-3-(5-nitro-2-thienyl)prop-2-en-1-one | MLS000703523 | SMR000322939 | cid_6012169
Type:
Small organic molecule
Emp. Form.:
C14H18N2O3S
Mol. Mass.:
294.369
SMILES:
CC1CC(C)CN(C1)C(=O)\C=C\c1ccc(s1)[N+]([O-])=O
Structure:
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