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Target
Regulator of G-protein signaling 16
Ligand
BDBM47797
Substrate
n/a
Meas. Tech.
Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 16
Synonyms:
RGS16 | RGS16_HUMAN | RGSR | Regulator of G-protein signaling 16 (RGS16) | regulator of G-protein signalling 16
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22748.87
Organism:
Homo sapiens (Human)
Description:
gi_156416009
Residue:
202
Sequence:
MCRTLAAFPTTCLERAKEFKTRLGIFLHKSELGCDTGSTGKFEWGSKHSKENRNFSEDVLGWRESFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHQIFEEFICSEAPKEVNIDHETHELTRMNLQTATATCFDAAQGKTRTLMEKDSYPRFLKSPAYRDLAAQASAASATLSSCSLDEPSHT
  
Inhibitor
Name:
BDBM47797
Synonyms:
MLS000684930 | N-[2-[6-[2-(diethylamino)ethylamino]-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]ethyl]-4-methyl-benzenesulfonamide | N-[2-[6-[2-(diethylamino)ethylamino]-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]ethyl]-4-methylbenzenesulfonamide | SMR000324888 | cid_16194969
Type:
Small organic molecule
Emp. Form.:
C20H29N7O2S
Mol. Mass.:
431.555
SMILES:
CCN(CC)CCNc1ccc2nnc(CCNS(=O)(=O)c3ccc(C)cc3)n2n1
Structure:
Search PDB for entries with ligand similarity: