Reaction Details Report a problem with these data
Target
Regulator of G-protein signaling 16
Ligand
BDBM47799
Substrate
n/a
Meas. Tech.
Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 16
Synonyms:
RGS16 | RGS16_HUMAN | RGSR | Regulator of G-protein signaling 16 (RGS16) | regulator of G-protein signalling 16
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22748.87
Organism:
Homo sapiens (Human)
Description:
gi_156416009
Residue:
202
Sequence:
MCRTLAAFPTTCLERAKEFKTRLGIFLHKSELGCDTGSTGKFEWGSKHSKENRNFSEDVLGWRESFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHQIFEEFICSEAPKEVNIDHETHELTRMNLQTATATCFDAAQGKTRTLMEKDSYPRFLKSPAYRDLAAQASAASATLSSCSLDEPSHT
  
Inhibitor
Name:
BDBM47799
Synonyms:
2-(benzenesulfonyl)-N-[4-(2-pyrimidinylsulfamoyl)phenyl]acetamide | 2-(benzenesulfonyl)-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]acetamide | 2-(phenylsulfonyl)-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]ethanamide | 2-besyl-N-[4-(2-pyrimidylsulfamoyl)phenyl]acetamide | MLS000716743 | SMR000278260 | cid_4428810
Type:
Small organic molecule
Emp. Form.:
C18H16N4O5S2
Mol. Mass.:
432.473
SMILES:
O=C(CS(=O)(=O)c1ccccc1)Nc1ccc(cc1)S(=O)(=O)Nc1ncccn1
Structure:
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