Reaction Details Report a problem with these data
Target
Dual specificity protein phosphatase 3
Ligand
BDBM46217
Substrate
n/a
Meas. Tech.
SAR VHR1 absorbance Assay for In Vitro dose response studies.
IC50
37100±n/a nM
Citation
 PubChem, PC SAR VHR1 absorbance Assay for In Vitro dose response studies. PubChem Bioassay (2009)[AID] 
Target
Name:
Dual specificity protein phosphatase 3
Synonyms:
DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR
Type:
Hydrolase
Mol. Mass.:
20480.58
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
185
Sequence:
MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKEGKLKP
  
Inhibitor
Name:
BDBM46217
Synonyms:
2-(2-dibenzothiophenyloxy)-2-methylpropanoic acid | 2-dibenzothiophen-2-yloxy-2-methyl-propanoic acid | 2-dibenzothiophen-2-yloxy-2-methyl-propionic acid | 2-dibenzothiophen-2-yloxy-2-methylpropanoic acid | MLS-0412044.0001 | cid_901652
Type:
Small organic molecule
Emp. Form.:
C16H14O3S
Mol. Mass.:
286.346
SMILES:
CC(C)(Oc1ccc2sc3ccccc3c2c1)C(O)=O
Structure:
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