Reaction Details Report a problem with these data
Target
Estrogen receptor beta
Ligand
BDBM48313
Substrate
n/a
Meas. Tech.
Estrogen Receptor-beta Coactivator Binding Inhibitors Dose Response Confirmation
IC50
2919.45±n/a nM
Citation
 PubChem, PC Estrogen Receptor-beta Coactivator Binding Inhibitors Dose Response Confirmation PubChem Bioassay (2007)[AID] 
Target
Name:
Estrogen receptor beta
Synonyms:
ER-beta | ESR2 | ESR2_HUMAN | ESTRB | Estradiol receptor beta (ERβ) | Estrogen receptor | Estrogen receptor (ER beta) | Estrogen receptor beta | Estrogen receptor beta (ER beta) | Estrogen receptor beta (ER) | NR3A2 | Nuclear receptor subfamily 3 group A member 2 | estrogen beta
Type:
Protein
Mol. Mass.:
59238.43
Organism:
Homo sapiens (Human)
Description:
Q92731
Residue:
530
Sequence:
MDIKNSPSSLNSPSSYNCSQSILPLEHGSIYIPSSYVDSHHEYPAMTFYSPAVMNYSIPSNVTNLEGGPGRQTTSPNVLWPTPGHLSPLVVHRQLSHLYAEPQKSPWCEARSLEHTLPVNRETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVRELLLDALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVVPVYDLLLEMLNAHVLRGCKSSITGSECSPAEDSKSKEGSQNPQSQ
  
Inhibitor
Name:
BDBM48313
Synonyms:
MLS000068374 | N-[4-[2-(2-keto-2-morpholino-ethyl)tetrazol-5-yl]phenyl]-2-(2-thienyl)acetamide | N-[4-[2-(2-morpholin-4-yl-2-oxidanylidene-ethyl)-1,2,3,4-tetrazol-5-yl]phenyl]-2-thiophen-2-yl-ethanamide | N-[4-[2-(2-morpholin-4-yl-2-oxoethyl)tetrazol-5-yl]phenyl]-2-thiophen-2-ylacetamide | N-[4-[2-[2-(4-morpholinyl)-2-oxoethyl]-5-tetrazolyl]phenyl]-2-thiophen-2-ylacetamide | N-{4-[2-(2-Morpholin-4-yl-2-oxo-ethyl)-2H-tetrazol-5-yl]-phenyl}-2-thiophen-2-yl-acetamide | SMR000008456 | cid_652312
Type:
Small organic molecule
Emp. Form.:
C19H20N6O3S
Mol. Mass.:
412.465
SMILES:
O=C(Cc1cccs1)Nc1ccc(cc1)-c1nnn(CC(=O)N2CCOCC2)n1
Structure:
Search PDB for entries with ligand similarity: