Reaction Details Report a problem with these data
Target
Estrogen receptor beta
Ligand
BDBM48405
Substrate
n/a
Meas. Tech.
Estrogen Receptor-beta Coactivator Binding Inhibitors Dose Response Confirmation
IC50
2709.22±n/a nM
Citation
 PubChem, PC Estrogen Receptor-beta Coactivator Binding Inhibitors Dose Response Confirmation PubChem Bioassay (2007)[AID] 
Target
Name:
Estrogen receptor beta
Synonyms:
ER-beta | ESR2 | ESR2_HUMAN | ESTRB | Estradiol receptor beta (ERβ) | Estrogen receptor | Estrogen receptor (ER beta) | Estrogen receptor beta | Estrogen receptor beta (ER beta) | Estrogen receptor beta (ER) | NR3A2 | Nuclear receptor subfamily 3 group A member 2 | estrogen beta
Type:
Protein
Mol. Mass.:
59238.43
Organism:
Homo sapiens (Human)
Description:
Q92731
Residue:
530
Sequence:
MDIKNSPSSLNSPSSYNCSQSILPLEHGSIYIPSSYVDSHHEYPAMTFYSPAVMNYSIPSNVTNLEGGPGRQTTSPNVLWPTPGHLSPLVVHRQLSHLYAEPQKSPWCEARSLEHTLPVNRETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVRELLLDALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVVPVYDLLLEMLNAHVLRGCKSSITGSECSPAEDSKSKEGSQNPQSQ
  
Inhibitor
Name:
BDBM48405
Synonyms:
MLS000063217 | N-(4-piperidin-1-ylsulfonylphenyl)-2-thiophen-2-yl-ethanamide | N-(4-piperidin-1-ylsulfonylphenyl)-2-thiophen-2-ylacetamide | N-(4-piperidinosulfonylphenyl)-2-(2-thienyl)acetamide | N-[4-(1-piperidinylsulfonyl)phenyl]-2-(2-thienyl)acetamide | N-[4-(1-piperidinylsulfonyl)phenyl]-2-thiophen-2-ylacetamide | SMR000074757 | cid_1305863
Type:
Small organic molecule
Emp. Form.:
C17H20N2O3S2
Mol. Mass.:
364.482
SMILES:
O=C(Cc1cccs1)Nc1ccc(cc1)S(=O)(=O)N1CCCCC1
Structure:
Search PDB for entries with ligand similarity: