Reaction Details Report a problem with these data
Target
D(1B) dopamine receptor
Ligand
BDBM37721
Substrate
n/a
Meas. Tech.
Allosteric Modulators of D1 Receptors: Dose-dependent Counterscreen
EC50
0.0151±n/a nM
Citation
 PubChem, PC Allosteric Modulators of D1 Receptors: Dose-dependent Counterscreen PubChem Bioassay (2007)[AID] 
Target
Name:
D(1B) dopamine receptor
Synonyms:
D(5) dopamine receptor | D1beta dopamine receptor | DOPAMINE D5 | DRD1B | DRD1L2 | DRD5 | DRD5_HUMAN | dopamine receptor D5
Type:
Protein
Mol. Mass.:
52943.41
Organism:
Homo sapiens (Human)
Description:
P21918
Residue:
477
Sequence:
MLPPGSNGTAYPGQFALYQQLAQGNAVGGSAGAPPLGPSQVVTACLLTLLIIWTLLGNVLVCAAIVRSRHLRANMTNVFIVSLAVSDLFVALLVMPWKAVAEVAGYWPFGAFCDVWVAFDIMCSTASILNLCVISVDRYWAISRPFRYKRKMTQRMALVMVGLAWTLSILISFIPVQLNWHRDQAASWGGLDLPNNLANWTPWEEDFWEPDVNAENCDSSLNRTYAISSSLISFYIPVAIMIVTYTRIYRIAQVQIRRISSLERAAEHAQSCRSSAACAPDTSLRASIKKETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCSGHPEGPPAGFPCVSETTFDVFVWFGWANSSLNPVIYAFNADFQKVFAQLLGCSHFCSRTPVETVNISNELISYNQDIVFHKEIAAAYIHMMPNAVTPGNREVDNDEEEGPFDRMFQIYQTSPDGDPVAESVWELDCEGEISLDKITPFTPNGFH
  
Inhibitor
Name:
BDBM37721
Synonyms:
2-(3-chlorophenyl)-4-N-methyltriazole-4,5-diamine | 2-(3-chlorophenyl)-N-methyl-2H-1,2,3-triazole-4,5-diamine | 2-(3-chlorophenyl)-N4-methyl-1,2,3-triazole-4,5-diamine | 2-(3-chlorophenyl)-N4-methyltriazole-4,5-diamine | MLS000091276 | SMR000025838 | [5-amino-2-(3-chlorophenyl)triazol-4-yl]-methyl-amine | cid_3240793
Type:
Small organic molecule
Emp. Form.:
C9H10ClN5
Mol. Mass.:
223.662
SMILES:
CNc1nn(nc1N)-c1cccc(Cl)c1
Structure:
Search PDB for entries with ligand similarity: