Reaction Details Report a problem with these data
Target
D(1A) dopamine receptor
Ligand
BDBM40793
Substrate
n/a
Meas. Tech.
Allosteric Modulators of D1 Receptors: Dose-dependent Assay
EC50
0.0078±n/a nM
Citation
 PubChem, PC Allosteric Modulators of D1 Receptors: Dose-dependent Assay PubChem Bioassay (2007)[AID] 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DA D1 receptor | DOPAMINE D1 | DRD1 | DRD1_HUMAN | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A
Type:
Enzyme
Mol. Mass.:
49303.43
Organism:
Homo sapiens (Human)
Description:
P21728
Residue:
446
Sequence:
MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLAETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKNCQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGSGETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIETVSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
  
Inhibitor
Name:
BDBM40793
Synonyms:
MLS000076142 | N-(5-chloranyl-2-morpholin-4-yl-phenyl)pyrazine-2-carboxamide | N-(5-chloro-2-morpholin-4-ylphenyl)pyrazine-2-carboxamide | N-(5-chloro-2-morpholino-phenyl)pyrazinamide | N-[5-chloro-2-(4-morpholinyl)phenyl]-2-pyrazinecarboxamide | Pyrazine-2-carboxylic acid (5-chloro-2-morpholin-4-yl-phenyl)-amide | SMR000000810 | cid_647782
Type:
Small organic molecule
Emp. Form.:
C15H15ClN4O2
Mol. Mass.:
318.758
SMILES:
Clc1ccc(N2CCOCC2)c(NC(=O)c2cnccn2)c1
Structure:
Search PDB for entries with ligand similarity: