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Target
D(1A) dopamine receptor
Ligand
BDBM48990
Substrate
n/a
Meas. Tech.
Allosteric Modulators of D1 Receptors: Dose-dependent Assay
EC50
2.24e-05±n/a nM
Citation
 PubChem, PC Allosteric Modulators of D1 Receptors: Dose-dependent Assay PubChem Bioassay (2007)[AID] 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DA D1 receptor | DOPAMINE D1 | DRD1 | DRD1_HUMAN | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A
Type:
Enzyme
Mol. Mass.:
49303.43
Organism:
Homo sapiens (Human)
Description:
P21728
Residue:
446
Sequence:
MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLAETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKNCQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGSGETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIETVSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
  
Inhibitor
Name:
BDBM48990
Synonyms:
Cyclopropanecarboxylic acid (6-butyrylamino-pyridin-3-yl)-amide | MLS000033162 | N-(6-butyramido-3-pyridyl)cyclopropanecarboxamide | N-[6-(1-oxobutylamino)-3-pyridinyl]cyclopropanecarboxamide | N-[6-(butanoylamino)pyridin-3-yl]cyclopropanecarboxamide | SMR000005494 | cid_649641
Type:
Small organic molecule
Emp. Form.:
C13H17N3O2
Mol. Mass.:
247.293
SMILES:
CCCC(=O)Nc1ccc(NC(=O)C2CC2)cn1
Structure:
Search PDB for entries with ligand similarity: