Reaction Details Report a problem with these data
Target
D(1A) dopamine receptor
Ligand
BDBM48999
Substrate
n/a
Meas. Tech.
Allosteric Modulators of D1 Receptors: Dose-dependent Assay
EC50
0.00365±n/a nM
Citation
 PubChem, PC Allosteric Modulators of D1 Receptors: Dose-dependent Assay PubChem Bioassay (2007)[AID] 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DA D1 receptor | DOPAMINE D1 | DRD1 | DRD1_HUMAN | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A
Type:
Enzyme
Mol. Mass.:
49303.43
Organism:
Homo sapiens (Human)
Description:
P21728
Residue:
446
Sequence:
MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLAETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKNCQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGSGETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIETVSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
  
Inhibitor
Name:
BDBM48999
Synonyms:
2-[3-(2-Chloro-benzyl)-5-cyclopropyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-ylamino]-ethanol | 2-[[3-(2-chlorobenzyl)-5-cyclopropyl-triazolo[4,5-d]pyrimidin-7-yl]amino]ethanol | 2-[[3-[(2-chlorophenyl)methyl]-5-cyclopropyl-7-triazolo[4,5-d]pyrimidinyl]amino]ethanol | 2-[[3-[(2-chlorophenyl)methyl]-5-cyclopropyl-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl]amino]ethanol | 2-[[3-[(2-chlorophenyl)methyl]-5-cyclopropyltriazolo[4,5-d]pyrimidin-7-yl]amino]ethanol | MLS000075673 | SMR000007891 | cid_655125
Type:
Small organic molecule
Emp. Form.:
C16H17ClN6O
Mol. Mass.:
344.799
SMILES:
OCCNc1nc(nc2n(Cc3ccccc3Cl)nnc12)C1CC1
Structure:
Search PDB for entries with ligand similarity: