Reaction Details Report a problem with these data
Target
D(1A) dopamine receptor
Ligand
BDBM49001
Substrate
n/a
Meas. Tech.
Allosteric Modulators of D1 Receptors: Dose-dependent Assay
EC50
0.00233±n/a nM
Citation
 PubChem, PC Allosteric Modulators of D1 Receptors: Dose-dependent Assay PubChem Bioassay (2007)[AID] 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DA D1 receptor | DOPAMINE D1 | DRD1 | DRD1_HUMAN | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A
Type:
Enzyme
Mol. Mass.:
49303.43
Organism:
Homo sapiens (Human)
Description:
P21728
Residue:
446
Sequence:
MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLAETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKNCQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGSGETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIETVSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
  
Inhibitor
Name:
BDBM49001
Synonyms:
5-acetyl-2-methyl-6-(methylamino)-4-phenyl-3-pyridinecarbonitrile | 5-acetyl-2-methyl-6-(methylamino)-4-phenyl-nicotinonitrile | 5-acetyl-2-methyl-6-(methylamino)-4-phenylpyridine-3-carbonitrile | 5-ethanoyl-2-methyl-6-(methylamino)-4-phenyl-pyridine-3-carbonitrile | MLS000079688 | SMR000038380 | cid_657615
Type:
Small organic molecule
Emp. Form.:
C16H15N3O
Mol. Mass.:
265.3098
SMILES:
CNc1nc(C)c(C#N)c(-c2ccccc2)c1C(C)=O
Structure:
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