Reaction Details Report a problem with these data
Target
D(1A) dopamine receptor
Ligand
BDBM49026
Substrate
n/a
Meas. Tech.
Allosteric Modulators of D1 Receptors: Dose-dependent Assay
EC50
0.00314±n/a nM
Citation
 PubChem, PC Allosteric Modulators of D1 Receptors: Dose-dependent Assay PubChem Bioassay (2007)[AID] 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DA D1 receptor | DOPAMINE D1 | DRD1 | DRD1_HUMAN | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A
Type:
Enzyme
Mol. Mass.:
49303.43
Organism:
Homo sapiens (Human)
Description:
P21728
Residue:
446
Sequence:
MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLAETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKNCQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGSGETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIETVSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
  
Inhibitor
Name:
BDBM49026
Synonyms:
5-methyl-2-(2-pyridin-3-ylquinazolin-4-yl)pyrazol-3-amine | 5-methyl-2-[2-(3-pyridinyl)-4-quinazolinyl]-3-pyrazolamine | MLS000081694 | SMR000062258 | [5-methyl-2-[2-(3-pyridyl)quinazolin-4-yl]pyrazol-3-yl]amine | cid_675349
Type:
Small organic molecule
Emp. Form.:
C17H14N6
Mol. Mass.:
302.3333
SMILES:
Cc1cc(N)n(n1)-c1nc(nc2ccccc12)-c1cccnc1
Structure:
Search PDB for entries with ligand similarity: