Reaction Details Report a problem with these data
Target
D(1A) dopamine receptor
Ligand
BDBM47104
Substrate
n/a
Meas. Tech.
Allosteric Modulators of D1 Receptors: Dose-dependent Assay
EC50
0.00289±n/a nM
Citation
 PubChem, PC Allosteric Modulators of D1 Receptors: Dose-dependent Assay PubChem Bioassay (2007)[AID] 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DA D1 receptor | DOPAMINE D1 | DRD1 | DRD1_HUMAN | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A
Type:
Enzyme
Mol. Mass.:
49303.43
Organism:
Homo sapiens (Human)
Description:
P21728
Residue:
446
Sequence:
MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLAETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKNCQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGSGETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIETVSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
  
Inhibitor
Name:
BDBM47104
Synonyms:
MLS000092489 | N-(1,3-benzodioxol-5-yl)-2-(1-ethyl-2-oxidanylidene-quinolin-4-yl)sulfanyl-ethanamide | N-(1,3-benzodioxol-5-yl)-2-(1-ethyl-2-oxoquinolin-4-yl)sulfanylacetamide | N-(1,3-benzodioxol-5-yl)-2-[(1-ethyl-2-keto-4-quinolyl)thio]acetamide | N-(1,3-benzodioxol-5-yl)-2-[(1-ethyl-2-oxo-4-quinolinyl)thio]acetamide | N-1,3-benzodioxol-5-yl-2-[(1-ethyl-2-oxo-1,2-dihydroquinolin-4-yl)thio]acetamide | SMR000028039 | cid_3242817
Type:
Small organic molecule
Emp. Form.:
C20H18N2O4S
Mol. Mass.:
382.433
SMILES:
CCn1c2ccccc2c(SCC(=O)Nc2ccc3OCOc3c2)cc1=O
Structure:
Search PDB for entries with ligand similarity: