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Target
D(1A) dopamine receptor
Ligand
BDBM49058
Substrate
n/a
Meas. Tech.
Allosteric Modulators of D1 Receptors: Dose-dependent Assay
EC50
1.88e-06±n/a nM
Citation
 PubChem, PC Allosteric Modulators of D1 Receptors: Dose-dependent Assay PubChem Bioassay (2007)[AID] 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DA D1 receptor | DOPAMINE D1 | DRD1 | DRD1_HUMAN | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A
Type:
Enzyme
Mol. Mass.:
49303.43
Organism:
Homo sapiens (Human)
Description:
P21728
Residue:
446
Sequence:
MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLAETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKNCQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGSGETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIETVSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
  
Inhibitor
Name:
BDBM49058
Synonyms:
3-[(2-keto-3,4-dihydro-1H-quinolin-6-yl)sulfonylamino]-N-piperonyl-propionamide | MLS000092142 | N-(1,3-benzodioxol-5-ylmethyl)-3-[(2-oxidanylidene-3,4-dihydro-1H-quinolin-6-yl)sulfonylamino]propanamide | N-(1,3-benzodioxol-5-ylmethyl)-3-[(2-oxo-3,4-dihydro-1H-quinolin-6-yl)sulfonylamino]propanamide | N~1~-(1,3-benzodioxol-5-ylmethyl)-N~3~-[(2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)sulfonyl]-beta-alaninamide | SMR000027046 | cid_3243919
Type:
Small organic molecule
Emp. Form.:
C20H21N3O6S
Mol. Mass.:
431.462
SMILES:
O=C(CCNS(=O)(=O)c1ccc2NC(=O)CCc2c1)NCc1ccc2OCOc2c1
Structure:
Search PDB for entries with ligand similarity: