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Target
D(1A) dopamine receptor
Ligand
BDBM49070
Substrate
n/a
Meas. Tech.
Allosteric Modulators of D1 Receptors: Dose-dependent Assay
EC50
0.00446±n/a nM
Citation
 PubChem, PC Allosteric Modulators of D1 Receptors: Dose-dependent Assay PubChem Bioassay (2007)[AID] 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DA D1 receptor | DOPAMINE D1 | DRD1 | DRD1_HUMAN | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A
Type:
Enzyme
Mol. Mass.:
49303.43
Organism:
Homo sapiens (Human)
Description:
P21728
Residue:
446
Sequence:
MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLAETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKNCQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGSGETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIETVSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
  
Inhibitor
Name:
BDBM49070
Synonyms:
1-(1,3-benzodioxol-5-yl)-5-[(2-fluorobenzyl)thio]-1H-tetrazole | 1-(1,3-benzodioxol-5-yl)-5-[(2-fluorobenzyl)thio]tetrazole | 1-(1,3-benzodioxol-5-yl)-5-[(2-fluorophenyl)methylsulfanyl]-1,2,3,4-tetrazole | 1-(1,3-benzodioxol-5-yl)-5-[(2-fluorophenyl)methylsulfanyl]tetrazole | 1-(1,3-benzodioxol-5-yl)-5-[(2-fluorophenyl)methylthio]tetrazole | MLS000061962 | SMR000070823 | cid_573210
Type:
Small organic molecule
Emp. Form.:
C15H11FN4O2S
Mol. Mass.:
330.337
SMILES:
Fc1ccccc1CSc1nnnn1-c1ccc2OCOc2c1
Structure:
Search PDB for entries with ligand similarity: