Reaction Details Report a problem with these data
Target
Transcription factor p65
Ligand
BDBM43368
Substrate
n/a
Meas. Tech.
Name: High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Dose Response
EC50
59±n/a nM
Citation
 PubChem, PC Name: High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Dose Response PubChem Bioassay (2008)[AID] 
Target
Name:
Transcription factor p65
Synonyms:
NFKB3 | Nuclear factor NF-kappa-B | Nuclear factor NF-kappa-B p65 subunit | RELA | TF65_HUMAN | v-rel reticuloendotheliosis viral oncogene homolog A isoform 1
Type:
Enzyme
Mol. Mass.:
60211.92
Organism:
Homo sapiens (Human)
Description:
Q04206
Residue:
551
Sequence:
MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPTIKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQCVKKRDLEQAISQRIQTNNNPFQVPIEEQRGDYDLNAVRLCFQVTVRDPSGRPLRLPPVLSHPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFSQADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEEKRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINYDEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQAVAPPAPKPTQAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQLLNQGIPVAPHTTEPMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGLPNGLLSGDEDFSSIADMDFSALLSQISS
  
Inhibitor
Name:
BDBM43368
Synonyms:
(1-acetamido-2,2,2-trichloroethyl) N,N-dimethylcarbamodithioate | Dimethyl-dithiocarbamic acid 1-acetylamino-2,2,2-trichloro-ethyl ester | MLS000554830 | N,N-dimethylcarbamodithioic acid (1-acetamido-2,2,2-trichloro-ethyl) ester | N,N-dimethylcarbamodithioic acid (1-acetamido-2,2,2-trichloroethyl) ester | SMR000146947 | [1-acetamido-2,2,2-tris(chloranyl)ethyl] N,N-dimethylcarbamodithioate | cid_3490047
Type:
Small organic molecule
Emp. Form.:
C7H11Cl3N2OS2
Mol. Mass.:
309.664
SMILES:
CN(C)C(=S)SC(NC(C)=O)C(Cl)(Cl)Cl
Structure:
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