Reaction Details Report a problem with these data
Target
Transcription factor p65
Ligand
BDBM49856
Substrate
n/a
Meas. Tech.
Name: High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Dose Response
EC50
96±n/a nM
Citation
 PubChem, PC Name: High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Dose Response PubChem Bioassay (2008)[AID] 
Target
Name:
Transcription factor p65
Synonyms:
NFKB3 | Nuclear factor NF-kappa-B | Nuclear factor NF-kappa-B p65 subunit | RELA | TF65_HUMAN | v-rel reticuloendotheliosis viral oncogene homolog A isoform 1
Type:
Enzyme
Mol. Mass.:
60211.92
Organism:
Homo sapiens (Human)
Description:
Q04206
Residue:
551
Sequence:
MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPTIKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQCVKKRDLEQAISQRIQTNNNPFQVPIEEQRGDYDLNAVRLCFQVTVRDPSGRPLRLPPVLSHPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFSQADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEEKRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINYDEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQAVAPPAPKPTQAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQLLNQGIPVAPHTTEPMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGLPNGLLSGDEDFSSIADMDFSALLSQISS
  
Inhibitor
Name:
BDBM49856
Synonyms:
(Z)-1-(1,3-benzodioxol-5-yl)-3-(2-bromoanilino)-2-propen-1-one | (Z)-1-(1,3-benzodioxol-5-yl)-3-(2-bromoanilino)prop-2-en-1-one | (Z)-1-(1,3-benzodioxol-5-yl)-3-[(2-bromophenyl)amino]prop-2-en-1-one | MLS000709963 | SMR000287130 | cid_5345545
Type:
Small organic molecule
Emp. Form.:
C16H12BrNO3
Mol. Mass.:
346.175
SMILES:
Brc1ccccc1N=CCC(=O)c1ccc2OCOc2c1 |w:7.7|
Structure:
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