Reaction Details Report a problem with these data
Target
Transcription factor p65
Ligand
BDBM49987
Substrate
n/a
Meas. Tech.
Name: High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Dose Response
EC50
201±n/a nM
Citation
 PubChem, PC Name: High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Dose Response PubChem Bioassay (2008)[AID] 
Target
Name:
Transcription factor p65
Synonyms:
NFKB3 | Nuclear factor NF-kappa-B | Nuclear factor NF-kappa-B p65 subunit | RELA | TF65_HUMAN | v-rel reticuloendotheliosis viral oncogene homolog A isoform 1
Type:
Enzyme
Mol. Mass.:
60211.92
Organism:
Homo sapiens (Human)
Description:
Q04206
Residue:
551
Sequence:
MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPTIKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQCVKKRDLEQAISQRIQTNNNPFQVPIEEQRGDYDLNAVRLCFQVTVRDPSGRPLRLPPVLSHPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFSQADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEEKRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINYDEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQAVAPPAPKPTQAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQLLNQGIPVAPHTTEPMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGLPNGLLSGDEDFSSIADMDFSALLSQISS
  
Inhibitor
Name:
BDBM49987
Synonyms:
MLS000775145 | SMR000364885 | cid_16196816 | sulfuric acid;4-[(N''E)-N''-[4-(trifluoromethyl)benzylidene]hydrazino]benzoic acid | sulfuric acid;4-[(N'E)-N'-[4-(trifluoromethyl)benzylidene]hydrazino]benzoic acid | sulfuric acid;4-[2-[[4-(trifluoromethyl)phenyl]methylidene]hydrazinyl]benzoic acid | sulfuric acid;4-[N'-[4-(trifluoromethyl)benzylidene]hydrazino]benzoic acid
Type:
Small organic molecule
Emp. Form.:
C15H11F3N2O2
Mol. Mass.:
308.2552
SMILES:
OC(=O)c1ccc(cc1)N=NCc1ccc(cc1)C(F)(F)F |w:9.9|
Structure:
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