Reaction Details Report a problem with these data
Target
DNA repair protein RAD51 homolog 1
Ligand
BDBM43826
Substrate
n/a
Meas. Tech.
Homologous Recombination_Rad51_DNA binding assay
IC50
85000±n/a nM
Citation
 PubChem, PC Homologous Recombination_Rad51_DNA binding assay PubChem Bioassay (2008)[AID] 
Target
Name:
DNA repair protein RAD51 homolog 1
Synonyms:
RAD51 | RAD51A | RAD51_HUMAN | RECA
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36960.74
Organism:
Homo sapiens (Human)
Description:
gi_49168602
Residue:
339
Sequence:
MAMQMQLEANADTSVEEESFGPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAAMFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD
  
Inhibitor
Name:
BDBM43826
Synonyms:
2-[5-(diethylsulfamoyl)-1-(4-methoxyphenyl)benzimidazol-2-yl]sulfanylpropanamide | 2-[[5-(diethylsulfamoyl)-1-(4-methoxyphenyl)-2-benzimidazolyl]thio]propanamide | 2-[[5-(diethylsulfamoyl)-1-(4-methoxyphenyl)benzimidazol-2-yl]thio]propionamide | Aminoglycosides, 5 | MLS000568202 | SMR000154533 | cid_4884909
Type:
Small organic molecule
Emp. Form.:
C21H26N4O4S2
Mol. Mass.:
462.586
SMILES:
CCN(CC)S(=O)(=O)c1ccc2n(c(SC(C)C(N)=O)nc2c1)-c1ccc(OC)cc1
Structure:
Search PDB for entries with ligand similarity: