Reaction Details Report a problem with these data
Target
dTDP-4-dehydrorhamnose 3,5-epimerase
Ligand
BDBM39870
Substrate
n/a
Meas. Tech.
Rml C and D dose-response confirmation
IC50
540±n/a nM
Citation
 PubChem, PC Rml C and D dose-response confirmation PubChem Bioassay (2009)[AID] 
Target
Name:
dTDP-4-dehydrorhamnose 3,5-epimerase
Synonyms:
RMLC_MYCTO | dTDP-4-dehydrorhamnose 3,5-epimerase RmlC | rmlC | strM
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22306.68
Organism:
Mycobacterium tuberculosis H37Rv
Description:
gi_15610601
Residue:
202
Sequence:
MKARELDVPGAWEITPTIHVDSRGLFFEWLTDHGFRAFAGHSLDVRQVNCSVSSAGVLRGLHFAQLPPSQAKYVTCVSGSVFDVVVDIREGSPTFGRWDSVLLDDQDRRTIYVSEGLAHGFLALQDNSTVMYLCSAEYNPQREHTICATDPTLAVDWPLVDGAAPSLSDRDAAAPSFEDVRASGLLPRWEQTQRFIGEMRGT
  
Inhibitor
Name:
BDBM39870
Synonyms:
6-chloranyl-4-methyl-8-[(4-methylpiperidin-1-yl)methyl]-7-oxidanyl-chromen-2-one | 6-chloro-7-hydroxy-4-methyl-8-[(4-methyl-1-piperidinyl)methyl]-1-benzopyran-2-one | 6-chloro-7-hydroxy-4-methyl-8-[(4-methylpiperidin-1-yl)methyl]chromen-2-one | 6-chloro-7-hydroxy-4-methyl-8-[(4-methylpiperidino)methyl]coumarin | MLS000028358 | SMR000035481 | cid_5389207
Type:
Small organic molecule
Emp. Form.:
C17H20ClNO3
Mol. Mass.:
321.799
SMILES:
CC1CCN(Cc2c(O)c(Cl)cc3c(C)cc(=O)oc23)CC1
Structure:
Search PDB for entries with ligand similarity: