Reaction Details Report a problem with these data
Target
dTDP-4-dehydrorhamnose 3,5-epimerase
Ligand
BDBM51498
Substrate
n/a
Meas. Tech.
Rml C and D dose-response confirmation
IC50
677±n/a nM
Citation
 PubChem, PC Rml C and D dose-response confirmation PubChem Bioassay (2009)[AID] 
Target
Name:
dTDP-4-dehydrorhamnose 3,5-epimerase
Synonyms:
RMLC_MYCTO | dTDP-4-dehydrorhamnose 3,5-epimerase RmlC | rmlC | strM
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22306.68
Organism:
Mycobacterium tuberculosis H37Rv
Description:
gi_15610601
Residue:
202
Sequence:
MKARELDVPGAWEITPTIHVDSRGLFFEWLTDHGFRAFAGHSLDVRQVNCSVSSAGVLRGLHFAQLPPSQAKYVTCVSGSVFDVVVDIREGSPTFGRWDSVLLDDQDRRTIYVSEGLAHGFLALQDNSTVMYLCSAEYNPQREHTICATDPTLAVDWPLVDGAAPSLSDRDAAAPSFEDVRASGLLPRWEQTQRFIGEMRGT
  
Inhibitor
Name:
BDBM51498
Synonyms:
6-chloranyl-8-[(4-methylpiperazin-1-yl)methyl]-7-oxidanyl-4-propyl-chromen-2-one | 6-chloro-7-hydroxy-8-[(4-methyl-1-piperazinyl)methyl]-4-propyl-1-benzopyran-2-one | 6-chloro-7-hydroxy-8-[(4-methylpiperazin-1-yl)methyl]-4-propylchromen-2-one | 6-chloro-7-hydroxy-8-[(4-methylpiperazino)methyl]-4-propyl-coumarin | MLS000081046 | SMR000042925 | cid_5389495
Type:
Small organic molecule
Emp. Form.:
C18H23ClN2O3
Mol. Mass.:
350.84
SMILES:
CCCc1cc(=O)oc2c(CN3CCN(C)CC3)c(O)c(Cl)cc12
Structure:
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