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Target
dTDP-4-dehydrorhamnose 3,5-epimerase
Ligand
BDBM34592
Substrate
n/a
Meas. Tech.
Rml C and D dose-response confirmation
IC50
14006±n/a nM
Citation
 PubChem, PC Rml C and D dose-response confirmation PubChem Bioassay (2009)[AID] 
Target
Name:
dTDP-4-dehydrorhamnose 3,5-epimerase
Synonyms:
RMLC_MYCTO | dTDP-4-dehydrorhamnose 3,5-epimerase RmlC | rmlC | strM
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22306.68
Organism:
Mycobacterium tuberculosis H37Rv
Description:
gi_15610601
Residue:
202
Sequence:
MKARELDVPGAWEITPTIHVDSRGLFFEWLTDHGFRAFAGHSLDVRQVNCSVSSAGVLRGLHFAQLPPSQAKYVTCVSGSVFDVVVDIREGSPTFGRWDSVLLDDQDRRTIYVSEGLAHGFLALQDNSTVMYLCSAEYNPQREHTICATDPTLAVDWPLVDGAAPSLSDRDAAAPSFEDVRASGLLPRWEQTQRFIGEMRGT
  
Inhibitor
Name:
BDBM34592
Synonyms:
5,6-bis(azanyl)-3-tert-butyl-8-[2-(hydroxymethyl)piperidin-1-yl]-2-oxidanylidene-1H-pyrrolo[2,3-c][2,7]naphthyridine-9-carbonitrile | 5,6-diamino-3-tert-butyl-2-keto-8-(2-methylolpiperidino)-1H-pyrrolo[2,3-c][2,7]naphthyridine-9-carbonitrile | 5,6-diamino-3-tert-butyl-8-[2-(hydroxymethyl)-1-piperidinyl]-2-oxo-1H-pyrrolo[2,3-c][2,7]naphthyridine-9-carbonitrile | 5,6-diamino-3-tert-butyl-8-[2-(hydroxymethyl)piperidin-1-yl]-2-oxo-1H-pyrrolo[2,3-c][2,7]naphthyridine-9-carbonitrile | MLS000097492 | SMR000067074 | cid_2998196
Type:
Small organic molecule
Emp. Form.:
C21H27N7O2
Mol. Mass.:
409.4848
SMILES:
CC(C)(C)N1C(=O)Cc2c1nc(N)c1c(N)nc(N3CCCCC3CO)c(C#N)c21
Structure:
Search PDB for entries with ligand similarity: