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Target
dTDP-4-dehydrorhamnose 3,5-epimerase
Ligand
BDBM50830
Substrate
n/a
Meas. Tech.
Rml C and D dose-response confirmation
IC50
855±n/a nM
Citation
 PubChem, PC Rml C and D dose-response confirmation PubChem Bioassay (2009)[AID] 
Target
Name:
dTDP-4-dehydrorhamnose 3,5-epimerase
Synonyms:
RMLC_MYCTO | dTDP-4-dehydrorhamnose 3,5-epimerase RmlC | rmlC | strM
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22306.68
Organism:
Mycobacterium tuberculosis H37Rv
Description:
gi_15610601
Residue:
202
Sequence:
MKARELDVPGAWEITPTIHVDSRGLFFEWLTDHGFRAFAGHSLDVRQVNCSVSSAGVLRGLHFAQLPPSQAKYVTCVSGSVFDVVVDIREGSPTFGRWDSVLLDDQDRRTIYVSEGLAHGFLALQDNSTVMYLCSAEYNPQREHTICATDPTLAVDWPLVDGAAPSLSDRDAAAPSFEDVRASGLLPRWEQTQRFIGEMRGT
  
Inhibitor
Name:
BDBM50830
Synonyms:
4-[[3-cyano-6-(3-pyridinyl)-2-pyridinyl]thio]-3-oxobutanoic acid ethyl ester | 4-[[3-cyano-6-(3-pyridyl)-2-pyridyl]thio]-3-keto-butyric acid ethyl ester | MLS000050698 | SMR000078165 | cid_1850575 | ethyl 4-(3-cyano-6-pyridin-3-yl-pyridin-2-yl)sulfanyl-3-oxidanylidene-butanoate | ethyl 4-(3-cyano-6-pyridin-3-ylpyridin-2-yl)sulfanyl-3-oxobutanoate | ethyl 4-[(5-cyano-2,3'-bipyridin-6-yl)thio]-3-oxobutanoate
Type:
Small organic molecule
Emp. Form.:
C17H15N3O3S
Mol. Mass.:
341.384
SMILES:
CCOC(=O)CC(=O)CSc1nc(ccc1C#N)-c1cccnc1
Structure:
Search PDB for entries with ligand similarity: