Reaction Details Report a problem with these data
Target
dTDP-4-dehydrorhamnose 3,5-epimerase
Ligand
BDBM51583
Substrate
n/a
Meas. Tech.
Rml C and D dose-response confirmation
IC50
447±n/a nM
Citation
 PubChem, PC Rml C and D dose-response confirmation PubChem Bioassay (2009)[AID] 
Target
Name:
dTDP-4-dehydrorhamnose 3,5-epimerase
Synonyms:
RMLC_MYCTO | dTDP-4-dehydrorhamnose 3,5-epimerase RmlC | rmlC | strM
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22306.68
Organism:
Mycobacterium tuberculosis H37Rv
Description:
gi_15610601
Residue:
202
Sequence:
MKARELDVPGAWEITPTIHVDSRGLFFEWLTDHGFRAFAGHSLDVRQVNCSVSSAGVLRGLHFAQLPPSQAKYVTCVSGSVFDVVVDIREGSPTFGRWDSVLLDDQDRRTIYVSEGLAHGFLALQDNSTVMYLCSAEYNPQREHTICATDPTLAVDWPLVDGAAPSLSDRDAAAPSFEDVRASGLLPRWEQTQRFIGEMRGT
  
Inhibitor
Name:
BDBM51583
Synonyms:
2-furancarboxylic acid [3-(2-methoxy-2-oxoethyl)-4-methyl-2-oxo-1-benzopyran-7-yl] ester | 3-(2-methoxy-2-oxoethyl)-4-methyl-2-oxo-2H-chromen-7-yl 2-furoate | MLS000050916 | SMR000078625 | [3-(2-methoxy-2-oxidanylidene-ethyl)-4-methyl-2-oxidanylidene-chromen-7-yl] furan-2-carboxylate | [3-(2-methoxy-2-oxoethyl)-4-methyl-2-oxochromen-7-yl] furan-2-carboxylate | cid_1242618 | furan-2-carboxylic acid [2-keto-3-(2-keto-2-methoxy-ethyl)-4-methyl-chromen-7-yl] ester
Type:
Small organic molecule
Emp. Form.:
C18H14O7
Mol. Mass.:
342.2996
SMILES:
COC(=O)Cc1c(C)c2ccc(OC(=O)c3ccco3)cc2oc1=O
Structure:
Search PDB for entries with ligand similarity: