Reaction Details Report a problem with these data
Target
dTDP-4-dehydrorhamnose 3,5-epimerase
Ligand
BDBM51678
Substrate
n/a
Meas. Tech.
Rml C and D dose-response confirmation
IC50
6905±n/a nM
Citation
 PubChem, PC Rml C and D dose-response confirmation PubChem Bioassay (2009)[AID] 
Target
Name:
dTDP-4-dehydrorhamnose 3,5-epimerase
Synonyms:
RMLC_MYCTO | dTDP-4-dehydrorhamnose 3,5-epimerase RmlC | rmlC | strM
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22306.68
Organism:
Mycobacterium tuberculosis H37Rv
Description:
gi_15610601
Residue:
202
Sequence:
MKARELDVPGAWEITPTIHVDSRGLFFEWLTDHGFRAFAGHSLDVRQVNCSVSSAGVLRGLHFAQLPPSQAKYVTCVSGSVFDVVVDIREGSPTFGRWDSVLLDDQDRRTIYVSEGLAHGFLALQDNSTVMYLCSAEYNPQREHTICATDPTLAVDWPLVDGAAPSLSDRDAAAPSFEDVRASGLLPRWEQTQRFIGEMRGT
  
Inhibitor
Name:
BDBM51678
Synonyms:
MLS000565982 | N'-[(Z)-(4-chloranyl-2-phenylimino-1,3-thiazol-5-ylidene)methyl]-2-(2-ethoxyphenoxy)ethanehydrazide | N'-[(Z)-(4-chloro-2-phenylimino-1,3-thiazol-5-ylidene)methyl]-2-(2-ethoxyphenoxy)acetohydrazide | N'-[(Z)-(4-chloro-2-phenylimino-3-thiazolin-5-ylidene)methyl]-2-(2-ethoxyphenoxy)acetohydrazide | N'-[(Z)-(4-chloro-2-phenylimino-5-thiazolylidene)methyl]-2-(2-ethoxyphenoxy)acetohydrazide | SMR000153122 | cid_6181153
Type:
Small organic molecule
Emp. Form.:
C20H19ClN4O3S
Mol. Mass.:
430.908
SMILES:
CCOc1ccccc1OCC(=O)NN=Cc1sc(Nc2ccccc2)nc1Cl |w:14.14|
Structure:
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