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Target
dTDP-4-dehydrorhamnose 3,5-epimerase
Ligand
BDBM45527
Substrate
n/a
Meas. Tech.
Rml C and D dose-response confirmation
IC50
177±n/a nM
Citation
 PubChem, PC Rml C and D dose-response confirmation PubChem Bioassay (2009)[AID] 
Target
Name:
dTDP-4-dehydrorhamnose 3,5-epimerase
Synonyms:
RMLC_MYCTO | dTDP-4-dehydrorhamnose 3,5-epimerase RmlC | rmlC | strM
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22306.68
Organism:
Mycobacterium tuberculosis H37Rv
Description:
gi_15610601
Residue:
202
Sequence:
MKARELDVPGAWEITPTIHVDSRGLFFEWLTDHGFRAFAGHSLDVRQVNCSVSSAGVLRGLHFAQLPPSQAKYVTCVSGSVFDVVVDIREGSPTFGRWDSVLLDDQDRRTIYVSEGLAHGFLALQDNSTVMYLCSAEYNPQREHTICATDPTLAVDWPLVDGAAPSLSDRDAAAPSFEDVRASGLLPRWEQTQRFIGEMRGT
  
Inhibitor
Name:
BDBM45527
Synonyms:
(4-methyl-2-oxidanylidene-chromen-7-yl) 3-[1,3-bis(oxidanylidene)isoindol-2-yl]propanoate | (4-methyl-2-oxochromen-7-yl) 3-(1,3-dioxoisoindol-2-yl)propanoate | 3-(1,3-dioxo-2-isoindolyl)propanoic acid (4-methyl-2-oxo-1-benzopyran-7-yl) ester | 3-phthalimidopropionic acid (2-keto-4-methyl-chromen-7-yl) ester | 4-methyl-2-oxo-2H-chromen-7-yl 3-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propanoate | MLS000576119 | SMR000185143 | cid_1184687
Type:
Small organic molecule
Emp. Form.:
C21H15NO6
Mol. Mass.:
377.3469
SMILES:
Cc1cc(=O)oc2cc(OC(=O)CCN3C(=O)c4ccccc4C3=O)ccc12
Structure:
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