Reaction Details Report a problem with these data
Target
Regulator of G-protein signaling 4
Ligand
BDBM47789
Substrate
n/a
Meas. Tech.
Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS4-Galphao.
EC50
30000±n/a nM
Citation
 PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS4-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 4
Synonyms:
RGP4 | RGS4 | RGS4_HUMAN | Regulator of G-protein signaling 4 (RGS4)
Type:
Enzyme
Mol. Mass.:
23263.51
Organism:
Homo sapiens (Human)
Description:
P49798
Residue:
205
Sequence:
MCKGLAGLPASCLRSAKDMKHRLGFLLQKSDSCEHNSSHNKKDKVVICQRVSQEEVKKWAESLENLISHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIKSPSKLSPKAKKIYNEFISVQATKEVNLDSCTREETSRNMLEPTITCFDEAQKKIFNLMEKDSYRRFLKSRFYLDLVNPSSCGAEKQKGAKSSADCASLVPQCA
  
Inhibitor
Name:
BDBM47789
Synonyms:
1-(2-chloranyl-4-nitro-phenyl)-3-methyl-piperazine;hydrochloride | 1-(2-chloro-4-nitro-phenyl)-3-methyl-piperazine;hydrochloride | 1-(2-chloro-4-nitrophenyl)-3-methylpiperazine;hydrochloride | MLS000722903 | SMR000304898 | cid_2771392
Type:
Small organic molecule
Emp. Form.:
C11H14ClN3O2
Mol. Mass.:
255.701
SMILES:
CC1CN(CCN1)c1ccc(cc1Cl)[N+]([O-])=O
Structure:
Search PDB for entries with ligand similarity: