Reaction Details Report a problem with these data
Target
Dual specificity protein phosphatase 3
Ligand
BDBM51765
Substrate
n/a
Meas. Tech.
Fluorescent assay for identification of compounds that inhibit VHR1
IC50
8290±n/a nM
Citation
 PubChem, PC Fluorescent assay for identification of compounds that inhibit VHR1 PubChem Bioassay (2009)[AID] 
Target
Name:
Dual specificity protein phosphatase 3
Synonyms:
DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR
Type:
Hydrolase
Mol. Mass.:
20480.58
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
185
Sequence:
MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKEGKLKP
  
Inhibitor
Name:
BDBM51765
Synonyms:
MLS000573736 | SMR000184584 | cid_23701559 | sodium 3-[2-(2-thioxobutylidene)-1,3-benzothiazol-3(2H)-yl]-1-propanesulfonate | sodium;3-[(2Z)-2-(2-sulfanylidenebutylidene)-1,3-benzothiazol-3-yl]-1-propanesulfonate | sodium;3-[(2Z)-2-(2-sulfanylidenebutylidene)-1,3-benzothiazol-3-yl]propane-1-sulfonate | sodium;3-[(2Z)-2-(2-thioxobutylidene)-1,3-benzothiazol-3-yl]propane-1-sulfonate
Type:
Small organic molecule
Emp. Form.:
C14H16NO3S3
Mol. Mass.:
342.477
SMILES:
CCC(=S)C=C1Sc2ccccc2N1CCCS([O-])(=O)=O |w:4.3|
Structure:
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