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Target
Zinc finger protein mex-5
Ligand
BDBM52167
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2
EC50
300000±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2 PubChem Bioassay (2009)[AID] 
Target
Name:
Zinc finger protein mex-5
Synonyms:
MEX5_CAEEL | RecName: Full=Zinc finger protein mex-5 | mex-5
Type:
Enzyme Catalytic Domain
Mol. Mass.:
52832.78
Organism:
Caenorhabditis elegans
Description:
gi_55976631
Residue:
468
Sequence:
MKAASNSVSSAGGSVSPTTTQPPLPPGQSSHPQIYDQQMQYYFAAAMPNQPMATYAAQNGSSQQYAPAAPYYQDANGQYVQVPANGSMAPQQHMMVSGQPYLYMAQPQQGAQQVMQSGQPQLIYYQQSMAPQAAPMYFHPMQAAPMLPEQMGVMPHTQPAIPPQQQPRQVGVEISSTRTAPLTSSTPLPTSLEYETVQRDNRNRNIQFRYHRVMEHDELPIDEISKITLDNHNDDTMSAEKENHFHEHRGEKFGRRGFPIPETDSQQPPNYKTRLCMMHASGIKPCDMGARCKFAHGLKELRATDAPARYPNNKYKTKLCKNFARGGTGFCPYGLRCEFVHPTDKEFQNIPPYQRMSHDDQDYDQDVIPEDYVVARHQPRFMRTGGRATTPTKVMLKHRNVAGSMMCLSNAGRDLQAGGDYNQPESNEDDLPPHLRRNRRENPPMNKRRTSLSTKWTSEENLGLRGHY
  
Inhibitor
Name:
BDBM52167
Synonyms:
2-amino-4-[2-(4-fluorobenzyl)oxy-3-methoxy-phenyl]-7-(2-furyl)-5-keto-4,6,7,8-tetrahydrochromene-3-carbonitrile | 2-amino-4-[2-[(4-fluorophenyl)methoxy]-3-methoxyphenyl]-7-(2-furanyl)-5-oxo-4,6,7,8-tetrahydro-1-benzopyran-3-carbonitrile | 2-amino-4-[2-[(4-fluorophenyl)methoxy]-3-methoxyphenyl]-7-(furan-2-yl)-5-oxo-4,6,7,8-tetrahydrochromene-3-carbonitrile | 2-amino-4-{2-[(4-fluorobenzyl)oxy]-3-methoxyphenyl}-7-(2-furyl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile | 2-azanyl-4-[2-[(4-fluorophenyl)methoxy]-3-methoxy-phenyl]-7-(furan-2-yl)-5-oxidanylidene-4,6,7,8-tetrahydrochromene-3-carbonitrile | MLS000043818 | SMR000021029 | cid_3241719
Type:
Small organic molecule
Emp. Form.:
C28H23FN2O5
Mol. Mass.:
486.491
SMILES:
COc1cccc(C2C(C#N)C(=N)OC3=C2C(=O)CC(C3)c2ccco2)c1OCc1ccc(F)cc1 |c:14|
Structure:
Search PDB for entries with ligand similarity: