Reaction Details Report a problem with these data
Target
Zinc finger protein mex-5
Ligand
BDBM41372
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2
EC50
300000±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2 PubChem Bioassay (2009)[AID] 
Target
Name:
Zinc finger protein mex-5
Synonyms:
MEX5_CAEEL | RecName: Full=Zinc finger protein mex-5 | mex-5
Type:
Enzyme Catalytic Domain
Mol. Mass.:
52832.78
Organism:
Caenorhabditis elegans
Description:
gi_55976631
Residue:
468
Sequence:
MKAASNSVSSAGGSVSPTTTQPPLPPGQSSHPQIYDQQMQYYFAAAMPNQPMATYAAQNGSSQQYAPAAPYYQDANGQYVQVPANGSMAPQQHMMVSGQPYLYMAQPQQGAQQVMQSGQPQLIYYQQSMAPQAAPMYFHPMQAAPMLPEQMGVMPHTQPAIPPQQQPRQVGVEISSTRTAPLTSSTPLPTSLEYETVQRDNRNRNIQFRYHRVMEHDELPIDEISKITLDNHNDDTMSAEKENHFHEHRGEKFGRRGFPIPETDSQQPPNYKTRLCMMHASGIKPCDMGARCKFAHGLKELRATDAPARYPNNKYKTKLCKNFARGGTGFCPYGLRCEFVHPTDKEFQNIPPYQRMSHDDQDYDQDVIPEDYVVARHQPRFMRTGGRATTPTKVMLKHRNVAGSMMCLSNAGRDLQAGGDYNQPESNEDDLPPHLRRNRRENPPMNKRRTSLSTKWTSEENLGLRGHY
  
Inhibitor
Name:
BDBM41372
Synonyms:
1,5-dimethyl-N-(3-morpholin-4-ylpropyl)-4-oxidanylidene-pyrrolo[3,2-c]quinoline-2-carboxamide | 1,5-dimethyl-N-(3-morpholin-4-ylpropyl)-4-oxopyrrolo[3,2-c]quinoline-2-carboxamide | 1,5-dimethyl-N-[3-(4-morpholinyl)propyl]-4-oxo-2-pyrrolo[3,2-c]quinolinecarboxamide | 4-keto-1,5-dimethyl-N-(3-morpholinopropyl)pyrrolo[3,2-c]quinoline-2-carboxamide | MLS000118084 | SMR000095032 | cid_5309031
Type:
Small organic molecule
Emp. Form.:
C21H26N4O3
Mol. Mass.:
382.4561
SMILES:
Cn1c(cc2c1c1ccccc1n(C)c2=O)C(=O)NCCCN1CCOCC1
Structure:
Search PDB for entries with ligand similarity: