Reaction Details Report a problem with these data
Target
Zinc finger protein mex-5
Ligand
BDBM29689
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2
EC50
10397±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2 PubChem Bioassay (2009)[AID] 
Target
Name:
Zinc finger protein mex-5
Synonyms:
MEX5_CAEEL | RecName: Full=Zinc finger protein mex-5 | mex-5
Type:
Enzyme Catalytic Domain
Mol. Mass.:
52832.78
Organism:
Caenorhabditis elegans
Description:
gi_55976631
Residue:
468
Sequence:
MKAASNSVSSAGGSVSPTTTQPPLPPGQSSHPQIYDQQMQYYFAAAMPNQPMATYAAQNGSSQQYAPAAPYYQDANGQYVQVPANGSMAPQQHMMVSGQPYLYMAQPQQGAQQVMQSGQPQLIYYQQSMAPQAAPMYFHPMQAAPMLPEQMGVMPHTQPAIPPQQQPRQVGVEISSTRTAPLTSSTPLPTSLEYETVQRDNRNRNIQFRYHRVMEHDELPIDEISKITLDNHNDDTMSAEKENHFHEHRGEKFGRRGFPIPETDSQQPPNYKTRLCMMHASGIKPCDMGARCKFAHGLKELRATDAPARYPNNKYKTKLCKNFARGGTGFCPYGLRCEFVHPTDKEFQNIPPYQRMSHDDQDYDQDVIPEDYVVARHQPRFMRTGGRATTPTKVMLKHRNVAGSMMCLSNAGRDLQAGGDYNQPESNEDDLPPHLRRNRRENPPMNKRRTSLSTKWTSEENLGLRGHY
  
Inhibitor
Name:
BDBM29689
Synonyms:
(4Z)-3-hydroxy-4-(2H-thiadiazol-5-ylidene)-1-cyclohexa-2,5-dienone | (4Z)-3-hydroxy-4-(2H-thiadiazol-5-ylidene)cyclohexa-2,5-dien-1-one | (4Z)-3-oxidanyl-4-(2H-1,2,3-thiadiazol-5-ylidene)cyclohexa-2,5-dien-1-one | 4-(1,2,3-thiadiazol-5-yl)-1,3-benzenediol | MLS000705525 | SMR000231800 | cid_5412886
Type:
Small organic molecule
Emp. Form.:
C8H6N2O2S
Mol. Mass.:
194.21
SMILES:
Oc1ccc(-c2cnns2)c(O)c1
Structure:
Search PDB for entries with ligand similarity: