Reaction Details Report a problem with these data
Target
Zinc finger protein mex-5
Ligand
BDBM53087
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2
EC50
253526±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2 PubChem Bioassay (2009)[AID] 
Target
Name:
Zinc finger protein mex-5
Synonyms:
MEX5_CAEEL | RecName: Full=Zinc finger protein mex-5 | mex-5
Type:
Enzyme Catalytic Domain
Mol. Mass.:
52832.78
Organism:
Caenorhabditis elegans
Description:
gi_55976631
Residue:
468
Sequence:
MKAASNSVSSAGGSVSPTTTQPPLPPGQSSHPQIYDQQMQYYFAAAMPNQPMATYAAQNGSSQQYAPAAPYYQDANGQYVQVPANGSMAPQQHMMVSGQPYLYMAQPQQGAQQVMQSGQPQLIYYQQSMAPQAAPMYFHPMQAAPMLPEQMGVMPHTQPAIPPQQQPRQVGVEISSTRTAPLTSSTPLPTSLEYETVQRDNRNRNIQFRYHRVMEHDELPIDEISKITLDNHNDDTMSAEKENHFHEHRGEKFGRRGFPIPETDSQQPPNYKTRLCMMHASGIKPCDMGARCKFAHGLKELRATDAPARYPNNKYKTKLCKNFARGGTGFCPYGLRCEFVHPTDKEFQNIPPYQRMSHDDQDYDQDVIPEDYVVARHQPRFMRTGGRATTPTKVMLKHRNVAGSMMCLSNAGRDLQAGGDYNQPESNEDDLPPHLRRNRRENPPMNKRRTSLSTKWTSEENLGLRGHY
  
Inhibitor
Name:
BDBM53087
Synonyms:
(5E)-5-(2-furanylmethylidene)-1-phenyl-2-sulfanylidene-1,3-diazinane-4,6-dione | (5E)-5-(2-furfurylidene)-1-phenyl-2-thioxo-hexahydropyrimidine-4,6-quinone | (5E)-5-(furan-2-ylmethylidene)-1-phenyl-2-sulfanylidene-1,3-diazinane-4,6-dione | 5-Furan-2-ylmethylene-1-phenyl-2-thioxo-dihydro-pyrimidine-4,6-dione | MLS001207185 | SMR000514454 | cid_1559791
Type:
Small organic molecule
Emp. Form.:
C15H10N2O3S
Mol. Mass.:
298.316
SMILES:
O=C1NC(=S)N(C(=O)C1=Cc1ccco1)c1ccccc1 |w:9.10|
Structure:
Search PDB for entries with ligand similarity: