Reaction Details Report a problem with these data
Target
POsterior Segregation
Ligand
BDBM52868
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA
EC50
300000±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA PubChem Bioassay (2009)[AID] 
Target
Name:
POsterior Segregation
Synonyms:
POsterior Segregation family member (pos-1)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29838.90
Organism:
Caenorhabditis elegans
Description:
gi_17562800
Residue:
264
Sequence:
MADNDFLSGEAIMVFKKEILDSHSDFTRSLSHQSASPEAYDQENVFSQDFQPFMKQDKETQNSASQPTSEQSLANRDPCTVPDDLREEMMRQRRKEDAFKTALCDAYKRSQACSYGDQCRFAHGVHELRLPMNPRGRNHPKYKTVLCDKFSMTGNCKYGTRCQFIHKIVDGNAAKLASGAHANTSSKSPARNAAAHNHSLFVPQGSTDRSMDLNQSLPIRQSDLVRAFARATRLDVSGYNSTAQLAQYFESQFQRIQQLSSHHH
  
Inhibitor
Name:
BDBM52868
Synonyms:
4-(2-Amino-3-cyano-pyrrolo[2,3-b]quinoxalin-1-yl)-benzoic acid | 4-(2-amino-3-cyano-1-pyrrolo[3,2-b]quinoxalinyl)benzoic acid | 4-(2-amino-3-cyano-pyrrolo[3,2-b]quinoxalin-1-yl)benzoic acid | 4-(2-amino-3-cyanopyrrolo[3,2-b]quinoxalin-1-yl)benzoic acid | 4-(2-azanyl-3-cyano-pyrrolo[3,2-b]quinoxalin-1-yl)benzoic acid | MLS000777296 | SMR000413689 | cid_705209
Type:
Small organic molecule
Emp. Form.:
C18H11N5O2
Mol. Mass.:
329.3122
SMILES:
Nc1c(C#N)c2nc3ccccc3nc2n1-c1ccc(cc1)C(O)=O
Structure:
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