Reaction Details Report a problem with these data
Target
POsterior Segregation
Ligand
BDBM52898
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA
EC50
300000±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA PubChem Bioassay (2009)[AID] 
Target
Name:
POsterior Segregation
Synonyms:
POsterior Segregation family member (pos-1)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29838.90
Organism:
Caenorhabditis elegans
Description:
gi_17562800
Residue:
264
Sequence:
MADNDFLSGEAIMVFKKEILDSHSDFTRSLSHQSASPEAYDQENVFSQDFQPFMKQDKETQNSASQPTSEQSLANRDPCTVPDDLREEMMRQRRKEDAFKTALCDAYKRSQACSYGDQCRFAHGVHELRLPMNPRGRNHPKYKTVLCDKFSMTGNCKYGTRCQFIHKIVDGNAAKLASGAHANTSSKSPARNAAAHNHSLFVPQGSTDRSMDLNQSLPIRQSDLVRAFARATRLDVSGYNSTAQLAQYFESQFQRIQQLSSHHH
  
Inhibitor
Name:
BDBM52898
Synonyms:
(4E)-4-[(2,4-dimethoxyanilino)methylene]-2-(6-methyl-2-pyridyl)isoquinoline-1,3-quinone | (4E)-4-[(2,4-dimethoxyanilino)methylidene]-2-(6-methyl-2-pyridinyl)isoquinoline-1,3-dione | (4E)-4-[(2,4-dimethoxyanilino)methylidene]-2-(6-methylpyridin-2-yl)isoquinoline-1,3-dione | (4E)-4-[[(2,4-dimethoxyphenyl)amino]methylidene]-2-(6-methylpyridin-2-yl)isoquinoline-1,3-dione | 4-[1-(2,4-Dimethoxy-phenylamino)-meth-(E)-ylidene]-2-(6-methyl-pyridin-2-yl)-4H-isoquinoline-1,3-dion e | MLS000762841 | SMR000439623 | cid_6356364
Type:
Small organic molecule
Emp. Form.:
C24H21N3O4
Mol. Mass.:
415.4412
SMILES:
COc1ccc(N=Cc2c(O)n(-c3cccc(C)n3)c(=O)c3ccccc23)c(OC)c1 |w:6.5|
Structure:
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