Reaction Details Report a problem with these data
Target
POsterior Segregation
Ligand
BDBM37077
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA
EC50
120247±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA PubChem Bioassay (2009)[AID] 
Target
Name:
POsterior Segregation
Synonyms:
POsterior Segregation family member (pos-1)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29838.90
Organism:
Caenorhabditis elegans
Description:
gi_17562800
Residue:
264
Sequence:
MADNDFLSGEAIMVFKKEILDSHSDFTRSLSHQSASPEAYDQENVFSQDFQPFMKQDKETQNSASQPTSEQSLANRDPCTVPDDLREEMMRQRRKEDAFKTALCDAYKRSQACSYGDQCRFAHGVHELRLPMNPRGRNHPKYKTVLCDKFSMTGNCKYGTRCQFIHKIVDGNAAKLASGAHANTSSKSPARNAAAHNHSLFVPQGSTDRSMDLNQSLPIRQSDLVRAFARATRLDVSGYNSTAQLAQYFESQFQRIQQLSSHHH
  
Inhibitor
Name:
BDBM37077
Synonyms:
4-[[7-(diethylamino)-2-keto-chromen-3-yl]amino]-4-keto-butyric acid | 4-[[7-(diethylamino)-2-oxidanylidene-chromen-3-yl]amino]-4-oxidanylidene-butanoic acid | 4-[[7-(diethylamino)-2-oxo-1-benzopyran-3-yl]amino]-4-oxobutanoic acid | 4-[[7-(diethylamino)-2-oxochromen-3-yl]amino]-4-oxobutanoic acid | 4-{[7-(diethylamino)-2-oxo-2H-chromen-3-yl]amino}-4-oxobutanoic acid | MLS000089659 | SMR000024277 | cid_3243384
Type:
Small organic molecule
Emp. Form.:
C17H20N2O5
Mol. Mass.:
332.3511
SMILES:
CCN(CC)c1ccc2cc(NC(=O)CCC(O)=O)c(=O)oc2c1
Structure:
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