Reaction Details Report a problem with these data
Target
POsterior Segregation
Ligand
BDBM52601
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA
EC50
300000±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA PubChem Bioassay (2009)[AID] 
Target
Name:
POsterior Segregation
Synonyms:
POsterior Segregation family member (pos-1)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29838.90
Organism:
Caenorhabditis elegans
Description:
gi_17562800
Residue:
264
Sequence:
MADNDFLSGEAIMVFKKEILDSHSDFTRSLSHQSASPEAYDQENVFSQDFQPFMKQDKETQNSASQPTSEQSLANRDPCTVPDDLREEMMRQRRKEDAFKTALCDAYKRSQACSYGDQCRFAHGVHELRLPMNPRGRNHPKYKTVLCDKFSMTGNCKYGTRCQFIHKIVDGNAAKLASGAHANTSSKSPARNAAAHNHSLFVPQGSTDRSMDLNQSLPIRQSDLVRAFARATRLDVSGYNSTAQLAQYFESQFQRIQQLSSHHH
  
Inhibitor
Name:
BDBM52601
Synonyms:
4-[3-[(1,3-diketoindan-2-ylidene)methyl]-2,5-dimethyl-pyrrol-1-yl]benzoic acid | 4-[3-[(1,3-dioxo-2-indenylidene)methyl]-2,5-dimethyl-1-pyrrolyl]benzoic acid | 4-[3-[(1,3-dioxoinden-2-ylidene)methyl]-2,5-dimethylpyrrol-1-yl]benzoic acid | 4-[3-[[1,3-bis(oxidanylidene)inden-2-ylidene]methyl]-2,5-dimethyl-pyrrol-1-yl]benzoic acid | 4-{3-[(1,3-dioxo-1,3-dihydro-2H-inden-2-ylidene)methyl]-2,5-dimethyl-1H-pyrrol-1-yl}benzoic acid | MLS000689985 | SMR000298711 | cid_1233277
Type:
Small organic molecule
Emp. Form.:
C23H17NO4
Mol. Mass.:
371.3854
SMILES:
[#6]-c1cc(\[#6]=[#6]-2/[#6](=O)-c3ccccc3-[#6]-2=O)c(-[#6])n1-c1ccc(cc1)-[#6](-[#8])=O
Structure:
Search PDB for entries with ligand similarity: