Reaction Details Report a problem with these data
Target
POsterior Segregation
Ligand
BDBM52705
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA
EC50
33327±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA PubChem Bioassay (2009)[AID] 
Target
Name:
POsterior Segregation
Synonyms:
POsterior Segregation family member (pos-1)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29838.90
Organism:
Caenorhabditis elegans
Description:
gi_17562800
Residue:
264
Sequence:
MADNDFLSGEAIMVFKKEILDSHSDFTRSLSHQSASPEAYDQENVFSQDFQPFMKQDKETQNSASQPTSEQSLANRDPCTVPDDLREEMMRQRRKEDAFKTALCDAYKRSQACSYGDQCRFAHGVHELRLPMNPRGRNHPKYKTVLCDKFSMTGNCKYGTRCQFIHKIVDGNAAKLASGAHANTSSKSPARNAAAHNHSLFVPQGSTDRSMDLNQSLPIRQSDLVRAFARATRLDVSGYNSTAQLAQYFESQFQRIQQLSSHHH
  
Inhibitor
Name:
BDBM52705
Synonyms:
(5E)-1-methyl-5-[(5-nitro-2-furanyl)methylidene]-1,3-diazinane-2,4,6-trione | (5E)-1-methyl-5-[(5-nitro-2-furyl)methylene]barbituric acid | (5E)-1-methyl-5-[(5-nitro-2-furyl)methylene]pyrimidine-2,4,6(1H,3H,5H)-trione | (5E)-1-methyl-5-[(5-nitrofuran-2-yl)methylidene]-1,3-diazinane-2,4,6-trione | (5Z)-1-methyl-5-[(5-nitro-2-furyl)methylene]barbituric acid | MLS000723836 | SMR000305431 | cid_1909603
Type:
Small organic molecule
Emp. Form.:
C10H7N3O6
Mol. Mass.:
265.1791
SMILES:
Cn1c(=O)[nH]c([O-])c([CH+]c2ccc(o2)[N+]([O-])=O)c1=O
Structure:
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