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Target
Heat shock cognate 71 kDa protein
Ligand
BDBM31709
Substrate
n/a
Meas. Tech.
High Throughput Screening Assay for Hsc70 Inhibitors
IC50
999000±n/a nM
Citation
 PubChem, PC High Throughput Screening Assay for Hsc70 Inhibitors PubChem Bioassay (2007)[AID] 
Target
Name:
Heat shock cognate 71 kDa protein
Synonyms:
HSC70 | HSP73 | HSP7C_HUMAN | HSPA10 | HSPA8 | heat shock 70kDa protein 8 isoform 1 | heat shock 70kDa protein 8 isoform 2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
70887.67
Organism:
Homo sapiens (Human)
Description:
gi_5729877
Residue:
646
Sequence:
MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSSMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKNSLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQKELEKVCNPIITKLYQSAGGMPGGMPGGFPGGGAPPSGGASSGPTIEEVD
  
Inhibitor
Name:
BDBM31709
Synonyms:
4-amino-2-phenyl-isoindoline-1,3-quinone | 4-amino-2-phenylisoindole-1,3-dione | 4-azanyl-2-phenyl-isoindole-1,3-dione | CHEMBL269410 | MLS000104009 | SMR000015725 | cid_3448473
Type:
Small organic molecule
Emp. Form.:
C14H10N2O2
Mol. Mass.:
238.2414
SMILES:
Nc1cccc2C(=O)N(C(=O)c12)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: