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Target
SUMO-conjugating enzyme UBC9
Ligand
BDBM61158
Substrate
n/a
Meas. Tech.
AlphaScreen confirmatory assay for validation of inhibitors of SUMOylation
IC50
540±n/a nM
Citation
 PubChem, PC AlphaScreen confirmatory assay for validation of inhibitors of SUMOylation PubChem Bioassay (2010)[AID] 
Target
Name:
SUMO-conjugating enzyme UBC9
Synonyms:
UBC9 | UBC9_HUMAN | UBCE9 | UBE2I | ubiquitin-conjugating enzyme E2I
Type:
Enzyme Catalytic Domain
Mol. Mass.:
18011.66
Organism:
Homo sapiens (Human)
Description:
gi_4507785
Residue:
158
Sequence:
MSGIALSRLAQERKAWRKDHPFGFVAVPTKNPDGTMNLMNWECAIPGKKGTPWEGGLFKLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSILEEDKDWRPAITIKQILLGIQELLNEPNIQDPAQAEAYTIYCQNRVEYEKRVRAQAKKFAPS
  
Inhibitor
Name:
BDBM61158
Synonyms:
1-(1-Phenylamino-but-3-enyl)-7-oxa-bicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylic acid dimethyl ester | 4-(1-anilinobut-3-enyl)-7-oxabicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylic acid dimethyl ester;hydrochloride | MLS000527128 | SMR000117602 | cid_9549553 | dimethyl 4-(1-anilinobut-3-enyl)-7-oxabicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylate;hydrochloride | dimethyl 4-(1-phenylazanylbut-3-enyl)-7-oxabicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylate;hydrochloride
Type:
Small organic molecule
Emp. Form.:
C20H21NO5
Mol. Mass.:
355.3844
SMILES:
[H]C12OC(C=C1)(C(CC=C)Nc1ccccc1)C(C(=O)OC)=C2C(=O)OC |c:4,23,TLB:23:22:2:4.5,THB:18:17:2:4.5|
Structure:
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