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Target
SUMO-conjugating enzyme UBC9
Ligand
BDBM47597
Substrate
n/a
Meas. Tech.
AlphaScreen confirmatory assay for validation of inhibitors of SUMOylation
IC50
1800±n/a nM
Citation
 PubChem, PC AlphaScreen confirmatory assay for validation of inhibitors of SUMOylation PubChem Bioassay (2010)[AID] 
Target
Name:
SUMO-conjugating enzyme UBC9
Synonyms:
UBC9 | UBC9_HUMAN | UBCE9 | UBE2I | ubiquitin-conjugating enzyme E2I
Type:
Enzyme Catalytic Domain
Mol. Mass.:
18011.66
Organism:
Homo sapiens (Human)
Description:
gi_4507785
Residue:
158
Sequence:
MSGIALSRLAQERKAWRKDHPFGFVAVPTKNPDGTMNLMNWECAIPGKKGTPWEGGLFKLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSILEEDKDWRPAITIKQILLGIQELLNEPNIQDPAQAEAYTIYCQNRVEYEKRVRAQAKKFAPS
  
Inhibitor
Name:
BDBM47597
Synonyms:
MLS000591719 | N-(12-Cyano-indolizino[2,3-b]quinoxalin-3-yl)-4-fluoro-benzamide | N-(12-cyano-3-indolizino[2,3-b]quinoxalinyl)-4-fluorobenzamide | N-(12-cyanoindolizino[2,3-b]quinoxalin-3-yl)-4-fluoranyl-benzamide | N-(12-cyanoindolizino[2,3-b]quinoxalin-3-yl)-4-fluoro-benzamide | N-(12-cyanoindolizino[2,3-b]quinoxalin-3-yl)-4-fluorobenzamide | SMR000218727 | cid_1867702
Type:
Small organic molecule
Emp. Form.:
C22H12FN5O
Mol. Mass.:
381.362
SMILES:
Fc1ccc(cc1)C(=O)Nc1ccc2c(C#N)c3nc4ccccc4nc3n2c1
Structure:
Search PDB for entries with ligand similarity: