Reaction Details Report a problem with these data
Target
SUMO-conjugating enzyme UBC9
Ligand
BDBM61179
Substrate
n/a
Meas. Tech.
AlphaScreen confirmatory assay for validation of inhibitors of SUMOylation
IC50
1900±n/a nM
Citation
 PubChem, PC AlphaScreen confirmatory assay for validation of inhibitors of SUMOylation PubChem Bioassay (2010)[AID] 
Target
Name:
SUMO-conjugating enzyme UBC9
Synonyms:
UBC9 | UBC9_HUMAN | UBCE9 | UBE2I | ubiquitin-conjugating enzyme E2I
Type:
Enzyme Catalytic Domain
Mol. Mass.:
18011.66
Organism:
Homo sapiens (Human)
Description:
gi_4507785
Residue:
158
Sequence:
MSGIALSRLAQERKAWRKDHPFGFVAVPTKNPDGTMNLMNWECAIPGKKGTPWEGGLFKLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSILEEDKDWRPAITIKQILLGIQELLNEPNIQDPAQAEAYTIYCQNRVEYEKRVRAQAKKFAPS
  
Inhibitor
Name:
BDBM61179
Synonyms:
2-(3,4-Dioxo-3,4-dihydro-naphthalen-1-ylamino)-benzoic acid | 2-[(3,4-diketo-1-naphthyl)amino]benzoic acid | 2-[(3,4-dioxo-1-naphthalenyl)amino]benzoic acid | 2-[(3,4-dioxonaphthalen-1-yl)amino]benzoic acid | 2-[[3,4-bis(oxidanylidene)naphthalen-1-yl]amino]benzoic acid | MLS000123143 | SMR000123743 | cid_3095208
Type:
Small organic molecule
Emp. Form.:
C17H11NO4
Mol. Mass.:
293.2735
SMILES:
OC(=O)c1ccccc1NC1=CC(=O)C(=O)c2ccccc12 |t:11|
Structure:
Search PDB for entries with ligand similarity: