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Target
SUMO-conjugating enzyme UBC9
Ligand
BDBM53174
Substrate
n/a
Meas. Tech.
AlphaScreen confirmatory assay for validation of inhibitors of SUMOylation
IC50
990±n/a nM
Citation
 PubChem, PC AlphaScreen confirmatory assay for validation of inhibitors of SUMOylation PubChem Bioassay (2010)[AID] 
Target
Name:
SUMO-conjugating enzyme UBC9
Synonyms:
UBC9 | UBC9_HUMAN | UBCE9 | UBE2I | ubiquitin-conjugating enzyme E2I
Type:
Enzyme Catalytic Domain
Mol. Mass.:
18011.66
Organism:
Homo sapiens (Human)
Description:
gi_4507785
Residue:
158
Sequence:
MSGIALSRLAQERKAWRKDHPFGFVAVPTKNPDGTMNLMNWECAIPGKKGTPWEGGLFKLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSILEEDKDWRPAITIKQILLGIQELLNEPNIQDPAQAEAYTIYCQNRVEYEKRVRAQAKKFAPS
  
Inhibitor
Name:
BDBM53174
Synonyms:
3,6-bis(2-furanyl)-1,2,4,5-tetrazine | 3,6-bis(2-furyl)-1,2,4,5-tetrazine | 3,6-bis(furan-2-yl)-1,2,4,5-tetrazine | MLS001175855 | SMR000589637 | cid_2554659
Type:
Small organic molecule
Emp. Form.:
C10H6N4O2
Mol. Mass.:
214.1802
SMILES:
c1coc(c1)-c1nnc(nn1)-c1ccco1
Structure:
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