Reaction Details Report a problem with these data
Target
Cell division control protein 42 homolog
Ligand
BDBM54675
Substrate
n/a
Meas. Tech.
Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 wildtype
EC50
30000±n/a nM
Citation
 PubChem, PC Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 wildtype PubChem Bioassay (2009)[AID] 
Target
Name:
Cell division control protein 42 homolog
Synonyms:
CDC42 | CDC42_HUMAN | Cell division control protein 42 homolog | G25K GTP-binding protein | cell division cycle 42 (GTP binding protein, 25kDa)
Type:
PROTEIN
Mol. Mass.:
21258.36
Organism:
Homo sapiens (Human)
Description:
ChEMBL_652970
Residue:
191
Sequence:
MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPPEPKKSRRCVLL
  
Inhibitor
Name:
BDBM54675
Synonyms:
(5Z)-5-(2-ketoindolin-3-ylidene)hydantoin | (5Z)-5-(2-oxidanylidene-1H-indol-3-ylidene)imidazolidine-2,4-dione | (5Z)-5-(2-oxo-1H-indol-3-ylidene)imidazolidine-2,4-dione | UNM-0000305761 | cid_15716919
Type:
Small organic molecule
Emp. Form.:
C11H7N3O3
Mol. Mass.:
229.1916
SMILES:
O=C1NC(=O)\C(N1)=C1\C(=O)Nc2ccccc12
Structure:
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